N-Methyl-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-D-alanine(CAS: 19914-38-6)

N-Methyl-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-D-alanine is a white or off-white crystalline powder with a molecular weight of approximately 219.29 g/mol. It is slightly soluble in water and miscible in common organic solvents. The compound is stable under normal conditions but can react with strong bases to form carboxylate salts. It has a melting point of 162-165°C.

N-Methyl-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-D-alanine can be synthesized through a multi-step process involving the protection of the carboxylic acid functionality, followed by esterification and subsequent deprotection. Commonly, a protecting group such as tert-butyldimethylsilyl (TBDMS) is used, and the reaction typically proceeds with good selectivity and yield under mild conditions.

N-Methyl-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-D-alanine is used in pharmaceuticals for the synthesis of various peptides and proteins. It is also applied in the production of polymers, where it can serve as a monomer or precursor for specific polymer modifications. Additionally, it has applications in the development of sensors and in semiconductor technology due to its chemical properties.

When handling N-Methyl-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-D-alanine, it is essential to wear appropriate personal protective equipment (PPE), such as gloves, safety goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize exposure. If a spill occurs, it should be immediately cleaned up using absorbent materials. Always consult the safety data sheet (SDS) for detailed information on handling and disposal.