Metoclopramide hydrochloride hydrate(CAS: 54143-57-6)

Metoclopramide hydrochloride hydrate is a medication used to treat gastrointestinal disorders. It is a hydrochloride salt of metoclopramide, which is a dopamine receptor antagonist. Its chemical formula is C17H22ClN3S·HCl·2H2O. It is typically a white to off-white crystalline powder with a bitter taste and is soluble in water.

Metoclopramide hydrochloride hydrate is primarily used to alleviate nausea, vomiting, and gastrointestinal motility issues. It is also employed in the treatment of chemotherapy-induced nausea and as an adjunct in managing postoperative nausea. In research, it is used to study gastrointestinal function and drug interactions.

Metoclopramide hydrochloride hydrate is generally considered safe when used as directed. However, it may cause side effects such as drowsiness, restlessness, or extrapyramidal symptoms. Proper handling and storage are essential to ensure safety, and it should be kept away from children and not used in excess. Safety standards for this compound are well-established in pharmaceutical guidelines.

Metoclopramide hydrochloride hydrate should be stored in a cool, dry place, away from direct light. It is best kept in a sealed container at a temperature below 25°C and humidity levels below 60%. Proper storage helps maintain its stability and potency over time.