(1R,3S,5s,7s)-5-Hydroxy-2-adamantanone(CAS: 20098-14-0)

(1R,3S,5s,7s)-5-Hydroxy-2-adamantanone (CAS: 20098-14-0) is a crystalline compound with a molecular weight of approximately 186.27 g/mol. It is slightly soluble in water but more soluble in organic solvents like ethanol and acetone. This compound exhibits moderate reactivity, particularly under basic conditions. It is often used in organic synthesis due to its unique structure and functional groups.

(1R,3S,5s,7s)-5-Hydroxy-2-adamantanone (CAS: 20098-14-0) can be synthesized via a multi-step process starting from 2-adamantanone. The synthesis involves reduction to form the hydroxy group, followed by stereoselective reduction using hydrogenation with a suitable catalyst, such as palladium on carbon. The overall yield is approximately 75-80%, and the reaction is highly selective, preserving the chirality of the compound.

(1R,3S,5s,7s)-5-Hydroxy-2-adamantanone (CAS: 20098-14-0) finds applications in the pharmaceutical industry for the synthesis of chiral intermediates, in polymer manufacturing for the development of special plastics, and in sensor technology for detecting specific chemical species. Additionally, it is used in semiconductor manufacturing for specific processing steps.

When handling (1R,3S,5s,7s)-5-Hydroxy-2-adamantanone (CAS: 20098-14-0), it is crucial to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. The compound should be stored in a cool, dry place away from direct sunlight. In case of a spill, immediately clean up with care, using appropriate safety protocols. Always refer to the safety data sheet (SDS) for detailed guidelines on handling and storage.