(3R)-Tetrahydro-3-furancarboxylic acid(CAS: 66838-42-4)

(3R)-Tetrahydro-3-furancarboxylic acid is a colorless crystalline solid with a molecular weight of approximately 128.12 g/mol. It is slightly soluble in water and has limited solubility in common organic solvents. This compound is known for its mild acidity and reactivity in acidic and basic conditions.

(3R)-Tetrahydro-3-furancarboxylic acid is synthesized through the reduction of 3-hydroxy-2-furanone. Common methods include catalytic hydrogenation using palladium on carbon or similar catalysts. The reaction is typically carried out in ethanol or water, yielding a high purity product with good selectivity and moderate to high yield.

(3R)-Tetrahydro-3-furancarboxylic acid is used in the pharmaceutical industry for the synthesis of certain drugs, and in the polymer industry as a monomer for the production of biodegradable polymers. It also finds applications in the development of sensors and as a precursor in the semiconductor industry.

When handling (3R)-Tetrahydro-3-furancarboxylic acid, it is important to wear appropriate personal protective equipment (PPE), including gloves, safety goggles, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood to avoid inhalation. Spills should be cleaned up using appropriate safety procedures, and the material safety data sheet (MSDS) should be referenced for specific safety information.