6-Hydroxy-7-methoxy-4(3H)-quinazolinone(CAS: 179688-52-9)

6-Hydroxy-7-methoxy-4(3H)-quinazolinone (CAS: 179688-52-9) is a crystalline solid with a molecular weight of approximately 246.22 g/mol. It has a solubility of about 0.1 g/L in water and is poorly soluble in organic solvents. This compound is moderately reactive, particularly towards nucleophiles and reducing agents. It can be isolated as a white to pale yellow crystalline solid.

6-Hydroxy-7-methoxy-4(3H)-quinazolinone (CAS: 179688-52-9) can be synthesized through the condensation of 4-chloroquinazoline with methanol in the presence of hydroxylamine followed by hydrolysis. The reaction is typically carried out in anhydrous conditions to improve yield and selectivity. The use of a suitable catalyst can enhance the reaction rate and product purity.

6-Hydroxy-7-methoxy-4(3H)-quinazolinone (CAS: 179688-52-9) finds applications in pharmaceuticals, particularly in the development of anti-inflammatory and antifungal drugs. It is also used in the synthesis of certain polymers and as a precursor in sensor technology and semiconductor manufacturing due to its unique chemical properties.

When handling 6-Hydroxy-7-methoxy-4(3H)-quinazolinone (CAS: 179688-52-9), it is essential to wear appropriate personal protective equipment (PPE) including gloves and safety goggles. Work should be performed in a well-ventilated area or under a fume hood to avoid inhalation of dust. In case of skin contact, immediately wash with soap and water. If swallowed, seek medical attention immediately. Always consult the Safety Data Sheet (SDS) for detailed handling and storage instructions to ensure safety in the laboratory setting.