Apigenin 7-O-Glucuronide(CAS: 29741-09-1)

Apigenin 7-O-Glucuronide (CAS: 29741-09-1) is a white crystalline powder with a molecular weight of approximately 454.47 g/mol. It has a melting point of 235-237°C and is slightly soluble in water. This compound exhibits limited reactivity under normal conditions, but its solubility and reactivity can be influenced by pH and temperature.

Apigenin 7-O-Glucuronide (CAS: 29741-09-1) is typically synthesized through enzymatic glucuronidation of apigenin using uridine diphosphate-glucuronosyltransferase. Common catalysts include UDP-glucuronosyltransferase isoforms, and the reaction is selective for the 7-OH group of apigenin, yielding a high yield of the glucuronide conjugate.

Apigenin 7-O-Glucuronide (CAS: 29741-09-1) is used in the pharmaceutical industry for drug development, particularly in the study of apigenin metabolism and pharmacokinetics. It is also relevant in environmental science for studying the transformation of apigenin in aquatic systems and in sensor technology for detecting apigenin-related metabolites.

When handling Apigenin 7-O-Glucuronide (CAS: 29741-09-1), it is essential to wear appropriate personal protective equipment (PPE) such as gloves and safety goggles. Store in a tightly closed container, away from direct sunlight and heat sources. Use a fume hood for all operations and ensure proper ventilation. In case of a spill, clean up with appropriate safety measures and consult the Safety Data Sheet (SDS) for further instructions.