4-(Aminomethyl)aniline(CAS: 4403-71-8)

4-(Aminomethyl)aniline (CAS: 4403-71-8) is a white crystalline solid at room temperature, with a molecular weight of approximately 121.14 g/mol. It is sparingly soluble in water but soluble in organic solvents like ethanol and acetone. Chemically, it is highly reactive due to the presence of a primary amine and an aromatic ring, making it susceptible to nucleophilic substitution and electrophilic aromatic substitution reactions.

4-(Aminomethyl)aniline (CAS: 4403-71-8) is commonly synthesized via the reduction of 4-chloromethylbenzene using sodium borohydride in aqueous media. The reaction is selective with a good yield, and the process involves a one-step reduction followed by workup and purification steps to isolate the desired product.

4-(Aminomethyl)aniline (CAS: 4403-71-8) is primarily used in the pharmaceutical industry for the synthesis of various drugs and intermediates. It is also utilized in the production of dyes and pigments, as well as in the development of sensors and semiconductors.

Handling 4-(Aminomethyl)aniline (CAS: 4403-71-8) requires strict safety measures. It should be stored in a cool, dry place away from direct sunlight and heat sources. Use appropriate personal protective equipment (PPE), such as gloves and eye protection. Work in a well-ventilated area or fume hood to prevent inhalation. In case of a spill, use appropriate containment and follow safety data sheet (SDS) guidelines for disposal.