1-(1-Benzylhexahydropyrrolo[3,4-b]pyrrol-5(1H)-yl)-2,2,2-trifluoroethanone(CAS: 1279822-87-5)

The compound 1-(1-Benzylhexahydropyrrolo[3,4-b]pyrrol-5(1H)-yl)-2,2,2-trifluoroethanone (CAS: 1279822-87-5) is a crystalline solid. It has a molecular weight of approximately 411.4 g/mol. The compound is poorly soluble in water but soluble in organic solvents like methanol and acetonitrile. Chemically, it is reactive towards nucleophiles and can undergo substitution reactions. It also exhibits basic properties and can form salts with acids.

1-(1-Benzylhexahydropyrrolo[3,4-b]pyrrol-5(1H)-yl)-2,2,2-trifluoroethanone (CAS: 1279822-87-5) is typically synthesized through a multi-step process involving the protection of the trifluoroethanol group, followed by the introduction of the benzyl hexahydropyrrolo[3,4-b]pyrrole moiety. The reaction often uses catalytic amounts of a palladium-based catalyst. The overall yield is around 70-80%, and the reaction is selective towards the desired product.

1-(1-Benzylhexahydropyrrolo[3,4-b]pyrrol-5(1H)-yl)-2,2,2-trifluoroethanone (CAS: 1279822-87-5) is used in the pharmaceutical industry for the synthesis of certain drug candidates due to its unique chemical structure. It also has potential applications in polymer chemistry, where its functionality can be exploited for copolymerization. Additionally, it may find use in the development of sensors and semiconductors.

When handling 1-(1-Benzylhexahydropyrrolo[3,4-b]pyrrol-5(1H)-yl)-2,2,2-trifluoroethanone (CAS: 1279822-87-5), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The substance should be handled in a fume hood to prevent inhalation. Spills should be cleaned up using appropriate absorbent materials and the area should be well ventilated. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.