Ferrozine(CAS: 69898-45-9)

Ferrozine is a stable, colorless compound that forms a deep blue complex with iron(II) ions. It has a molecular weight of approximately 288.16 g/mol and is poorly soluble in water. It is stable in air and light, making it useful for spectroscopic determinations of iron content. Ferrozine reacts selectively with iron(II) to form a highly colored complex, which can be measured spectrophotometrically.

Ferrozine is typically synthesized from 2-hydroxy-3,5-di-p-aminophenyl tetrazole and hydroxylamine. The synthesis involves the condensation reaction of these two reagents in the presence of a base. The process yields a high purity product with excellent selectivity for iron(II) ions.

Ferrozine is widely used in the pharmaceutical industry for iron content determination in drugs and supplements. It is also applied in the polymer industry for quality control and in the semiconductor industry for the detection of trace iron contamination. Additionally, it is employed in environmental monitoring for the analysis of iron in water and soil samples.

Ferrozine is generally considered safe but should be handled with care due to its nature of forming colored complexes. Always wear appropriate personal protective equipment (PPE), including gloves and safety goggles. Ensure that work is conducted in a well-ventilated area or fume hood. In case of spills, clear the area and clean up according to standard laboratory protocols. For more detailed information, refer to the Safety Data Sheet (SDS) for Ferrozine.