Methyl 5-hexynoate(CAS: 77758-51-1)

Methyl 5-hexynoate is a liquid with a molecular weight of approximately 114.13 g/mol. It has a boiling point of 112-114°C and a melting point of -23°C. The compound is slightly soluble in water and miscible with most organic solvents. It is mildly reactive and should be stored away from strong acids and bases.

Methyl 5-hexynoate can be synthesized via the Wittig reaction using hex-5-en-2-one and methyl iodide in the presence of a phosphonium salt as a catalyst. The reaction is typically carried out in an anhydrous organic solvent at room temperature, yielding a high selectivity and good yield.

Methyl 5-hexynoate is used in the fragrance and perfume industry as a flavor and aroma compound. It is also utilized in the synthesis of other chemical intermediates and as a reagent in some pharmaceutical processes.

When handling Methyl 5-hexynoate, appropriate personal protective equipment (PPE) such as gloves and safety goggles should be worn. The substance should be stored in a cool, dry place, away from strong acids and bases. In case of a spill, it should be cleaned up immediately using appropriate absorbents. Refer to the Safety Data Sheet (SDS) for detailed handling instructions and emergency procedures.