2-Bromo-1-(4-fluorophenyl)ethanone(CAS: 403-29-2)

2-Bromo-1-(4-fluorophenyl)ethanone (CAS: 403-29-2) is a white crystalline solid with a molecular weight of approximately 228.04 g/mol. It has a density of about 1.32 g/cm³ and is slightly soluble in water. The compound is known for its high reactivity, particularly in nucleophilic substitution reactions.

2-Bromo-1-(4-fluorophenyl)ethanone (CAS: 403-29-2) is typically synthesized via bromination of 1-(4-fluorophenyl)ethanone using a brominating agent like N-bromosuccinimide (NBS) in an organic solvent like acetonitrile. The reaction is often carried out under light or heat with a yield of about 70-80%.

2-Bromo-1-(4-fluorophenyl)ethanone (CAS: 403-29-2) is primarily used in the pharmaceutical industry for the synthesis of various medicinals. It also finds applications in the polymer industry for the preparation of specific polymer additives.

When handling 2-Bromo-1-(4-fluorophenyl)ethanone (CAS: 403-29-2), ensure the use of personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Handle under a fume hood to avoid inhalation. Store in a cool, dry place away from heat sources. In case of spill, neutralize with an appropriate chemical and dispose of according to local regulations. Refer to the Material Safety Data Sheet (MSDS) for detailed safety information.