Ethyl N-(2,3-dichloro-6-aminobenzyl)glcycine(CAS: 70406-92-7)

Ethyl N-(2,3-dichloro-6-aminobenzyl)glycine is a crystalline compound with a molecular weight of approximately 336.02 g/mol. It has a low solubility in water but is soluble in organic solvents like methanol and ethanol. The compound is reactive towards nucleophiles and can undergo substitution reactions. It is stable under normal storage conditions but should be protected from moisture and light.

Ethyl N-(2,3-dichloro-6-aminobenzyl)glycine can be synthesized through a multi-step process involving the synthesis of the 2,3-dichloro-6-aminobenzyl moiety and then coupling it with ethyl glycine chloride. Common reagents include sodium hydride and dichloromethane, with careful control over reaction conditions to achieve high yields and selectivity.

Ethyl N-(2,3-dichloro-6-aminobenzyl)glycine finds application in the pharmaceutical industry for the synthesis of active pharmaceutical ingredients. It is also used in the polymer industry for the development of special polymer additives and in the field of sensors for its reactivity towards certain analytes.

When handling Ethyl N-(2,3-dichloro-6-aminobenzyl)glycine, proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat is recommended. The compound should be handled in a well-ventilated area or a fume hood to avoid inhalation. Spills should be cleaned up using appropriate absorbents, and the area should be flushed with water. A safety data sheet (SDS) should be consulted for detailed emergency procedures.