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Sotorasib(CAS: 2296729-00-3)
CAS Number
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Basic Information
Molecular Formula
C30H30F2N6O3
Molecular Weight
560.59 g/mol
Physical Properties
Boiling Point
730.5±70.0 °C(Predicted)
Density
1.36±0.1 g/cm3(Predicted)
Water Solubility
Water : 33.33 mg/mL (59.46 mM; ultrasonic and adjust pH to 11 with NaOH)
Chemical Identifiers
SMILES
C=CC(=O)N1CCN([C@H](C1)C)c1nc(=O)n(c2c1cc(F)c(n2)c1c(O)cccc1F)c1c(C)ccnc1C(C)C
InChIKey
NXQKSXLFSAEQCZ-SFHVURJKSA-N
Database References
MDL Number
MFCD32062763
FAQ
Sotorasib, also known as LUM-201, is a selective inhibitor of KRAS G12C, a genetic mutation found in certain cancers. It has the molecular formula C28H25FN6O3. Sotorasib is a white or off-white powder with limited solubility in water and high solubility in organic solvents.
Sotorasib is primarily used as a therapeutic agent in the treatment of non-small cell lung cancer (NSCLC) with a specific KRAS G12C mutation. Clinical trials have demonstrated its effectiveness in this context, leading to its approval by regulatory bodies.
Sotorasib is considered generally safe when used under medical supervision. However, it may cause side effects such as nausea, vomiting, and diarrhea. Patients should follow medical advice and use the drug only as prescribed to minimize risks.
Sotorasib should be stored in a cool, dry place away from direct sunlight and heat sources. The optimal storage temperature is between 2°C and 8°C. It should be kept in original, tightly sealed containers to maintain its efficacy and stability.
Safety Notice
Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.
Always follow proper handling procedures
Contact Information
Contact Person
Manager Lu
luyan0021@163.com