2-Butyl-1,2-benzothiazol-3(2H)-one(CAS: 4299-07-4)

2-Butyl-1,2-benzothiazol-3(2H)-one is a crystalline solid with a molecular weight of approximately 212.28 g/mol. It has a solubility in water of 0.01 g/L and is soluble in organic solvents such as ethanol and acetone. Chemically, it is relatively stable but can undergo ring-opening reactions under basic conditions. It is also known for its ability to form complexes with metal ions.

2-Butyl-1,2-benzothiazol-3(2H)-one is typically synthesized via the condensation of 2-butylthioacetic acid with benzaldehyde, followed by ring closure. This process involves the use of a strong base like sodium hydroxide, and the yield is around 75-85%. The reaction is carried out under reflux in an aqueous alcohol mixture.

2-Butyl-1,2-benzothiazol-3(2H)-one finds applications in the pharmaceutical industry for its potential use as a medicinal intermediate. It is also utilized in the polymer industry for improving the thermal stability of polymers and in the sensor and semiconductor industries for its catalytic properties.

When handling 2-Butyl-1,2-benzothiazol-3(2H)-one, it is important to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be stored in a cool, dry place away from direct sunlight. In case of spill, it should be handled in a fume hood. Always refer to the Safety Data Sheet (SDS) for specific handling instructions and emergency procedures.