(6-Cyano-3-pyridinyl)boronic acid(CAS: 1011722-07-8)

(6-Cyano-3-pyridinyl)boronic acid is a crystalline solid with a molecular weight of approximately 233.12 g/mol. It has a melting point of 216-218°C and is slightly soluble in water. The compound shows reactivity towards nucleophiles and can participate in various chemical reactions, such as in organic synthesis and catalytic processes.

(6-Cyano-3-pyridinyl)boronic acid can be synthesized through the reaction of 3-pyridylboronic acid with cyanoacetic acid under appropriate conditions. Common methods include the use of stoichiometric amounts of base and heat to promote the reaction. The yield and selectivity can be optimized by adjusting the reaction conditions such as temperature and solvent.

(6-Cyano-3-pyridinyl)boronic acid is utilized in various industries, including pharmaceuticals, where it serves as a building block for drug synthesis, and in polymer chemistry, where it can be incorporated into polymer structures to enhance properties. It also finds applications in sensor technology and semiconductor manufacturing.

When handling (6-Cyano-3-pyridinyl)boronic acid, it is essential to use appropriate personal protective equipment (PPE) such as gloves and safety goggles. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up using appropriate environmental agents, and it is advisable to consult the Safety Data Sheet (SDS) for detailed instructions on handling and disposal.