(2E,4E)-2,4-Hexadienal(CAS: 142-83-6)

(2E,4E)-2,4-Hexadienal is a colorless liquid with a fruity odor. It has a molecular weight of approximately 112.18 g/mol and a boiling point of 154°C. The compound is slightly soluble in water but miscible with common organic solvents like ethanol and acetone. It is relatively stable under normal conditions and is susceptible to oxidation and hydrolysis, making it reactive in the presence of moisture or air.

(2E,4E)-2,4-Hexadienal can be synthesized via the Wittig reaction using 2-bromohexane and phenyltriphenylphosphonium bromide as reagents. This method offers good yield and selectivity. Other approaches include the Diels-Alder reaction between maleic anhydride and hexa-2,4-dien-1-ol. Catalytic hydrogenation of maleic anhydride is another route to produce the desired compound with high efficiency.

(2E,4E)-2,4-Hexadienal is primarily used in the fragrance and flavor industry due to its pleasant fruity aroma. It is also employed in the food and beverage sector as a flavor enhancer. Additionally, the compound finds applications in the pharmaceutical industry as a precursor for the synthesis of certain compounds. It is also used in the polymer and sensor technology sectors for its specific chemical reactivity and functionality.

When handling (2E,4E)-2,4-Hexadienal, it is essential to wear appropriate personal protective equipment (PPE), including gloves, safety goggles, and a lab coat. Ensure the area is well-ventilated, and avoid inhalation or skin contact. Store the compound in a cool, dry place away from heat and sources of ignition. In the case of a spill, immediately clean it up using appropriate absorbent materials and follow the safety data sheet (SDS) guidelines for disposal. Always refer to the SDS for detailed safety information.