6-Bromo-1-chloroisoquinoline(CAS: 205055-63-6)

6-Bromo-1-chloroisoquinoline is a crystalline solid with a molecular weight of approximately 234.03 g/mol. It is slightly soluble in water but more soluble in organic solvents like methanol and ethanol. Chemically, it is reactive towards nucleophiles and electrophiles, making it useful for various synthetic transformations.

6-Bromo-1-chloroisoquinoline is typically synthesized through the bromination of 1-chloroisocinoline followed by hydrogenation of the resulting bromoisoquinoline. Commonly used catalysts include palladium-based catalysts, and the overall yield can range from 70% to 80% depending on the reaction conditions.

6-Bromo-1-chloroisoquinoline is primarily used in the pharmaceutical industry for the synthesis of various bioactive compounds. It is also utilized in the chemical industry for the development of new materials and sensors. Its properties make it a valuable reagent in academic and industrial research.

When handling 6-Bromo-1-chloroisoquinoline, it is crucial to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. The compound should be stored in a closed container in a cool, dry place. In case of a spill, use a fume hood to handle the cleanup and refer to the Safety Data Sheet (SDS) for specific instructions.