Tetrahydro-2H-pyran-4-carboxylic acid(CAS: 5337-03-1)

Tetrahydro-2H-pyran-4-carboxylic acid, also known as 4-carboxy-2,3,4,6-tetrahydro-2H-pyran, is a colorless to white crystalline solid with a melting point of 73-74°C. It is soluble in water and has a pKa of about 4.6. This compound is widely used in organic synthesis as a building block and in pharmaceuticals for its reactive functionality.

Tetrahydro-2H-pyran-4-carboxylic acid is primarily used in the synthesis of drugs, as a precursor for various organic compounds, and in the pharmaceutical industry for developing new medications. It is also utilized in the formulation of resins and coatings, and as a reagent in organic chemistry.

Tetrahydro-2H-pyran-4-carboxylic acid is generally considered safe for laboratory use when proper protective measures are taken. It is non-flammable, but prolonged skin contact or inhalation of its vapors may cause irritation. It is important to handle it in a well-ventilated area and wear appropriate personal protective equipment such as gloves and goggles.

Tetrahydro-2H-pyran-4-carboxylic acid should be stored in a cool, dry place away from direct sunlight and heat sources. Keep the container tightly sealed to prevent moisture absorption. It is recommended to store it at a temperature below 30°C to maintain its stability and purity.