4-Phenoxyaniline(CAS: 139-59-3)

4-Phenoxyaniline (CAS: 139-59-3) is a white crystalline solid with a molecular weight of 164.19 g/mol. It has a melting point of 126-128°C and a boiling point of 288-290°C. The compound is soluble in water and ethanol. Chemically, it is moderately reactive, particularly towards electrophilic aromatic substitution reactions.

4-Phenoxyaniline (CAS: 139-59-3) is typically synthesized by the reduction of 4-chloroaniline with sodium borohydride in the presence of ethanol. The reaction is conducted in a 1:1 molar ratio with a yield of approximately 85%. The use of a catalyst such as sodium hydroxide can improve the selectivity and yield.

4-Phenoxyaniline (CAS: 139-59-3) is primarily used in the pharmaceutical industry for the synthesis of certain drugs. It is also utilized in the production of dyes, pigments, and as a precursor in the manufacturing of polymers and semiconductors.

When handling 4-Phenoxyaniline (CAS: 139-59-3), it is important to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be stored in a cool, well-ventilated area away from heat and flame. Spills should be cleaned up using absorbent materials and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed safety information.