1-(Aminooxy)-2,4-dinitrobenzene(CAS: 17508-17-7)

1-(Aminooxy)-2,4-dinitrobenzene is a crystalline solid with a high molecular weight of around 253.08 g/mol. It is slightly soluble in water and more soluble in organic solvents like ethanol and dimethylformamide. Chemically, it is highly reactive, especially towards nucleophilic substitution reactions. It is an important intermediate in the synthesis of various dyes, pharmaceuticals, and other organic compounds.

1-(Aminooxy)-2,4-dinitrobenzene is typically synthesized by the reaction of dinitrobenzene with hydroxylamine hydrochloride. The reaction involves the formation of a nitroso derivative, which then undergoes an intramolecular cyclization to form the aminooxy derivative. This process requires careful control of temperature and pH to achieve high yield and selectivity.

1-(Aminooxy)-2,4-dinitrobenzene is primarily used in the pharmaceutical industry as a precursor for the synthesis of various drugs. It is also utilized in the production of dyes and pigments, as well as in the development of sensors and semiconductors. Its reactivity and functionality make it a valuable intermediate in these applications.

When handling 1-(Aminooxy)-2,4-dinitrobenzene, it is essential to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to prevent inhalation of vapors. Spills should be cleaned up carefully using appropriate absorbent materials. Always consult the safety data sheet (SDS) for detailed emergency procedures and handling instructions.