4-Methyl-2-pentenoic acid(CAS: 10321-71-8)

4-Methyl-2-pentenoic acid is a crystalline solid with a molecular weight of approximately 112.13 g/mol. It has a pKa of around 2.4. The compound is slightly soluble in water and readily soluble in organic solvents such as ethanol and acetone. It is reactive towards bases and can undergo esterification and dehydration reactions.

4-Methyl-2-pentenoic acid is synthesized from 2-methyl-2-pentene via a hydrohalogenation followed by hydrolysis. Commonly, this involves treating the alkene with a mixture of concentrated sulfuric acid and water. The method yields a mixture of isomers, requiring subsequent separation and purification steps.

4-Methyl-2-pentenoic acid is primarily used in the pharmaceutical industry for the synthesis of certain drugs. It is also utilized in the polymer industry for the development of new copolymers and in the sensor industry for the fabrication of gas sensors. Other applications include its use in analytical chemistry and as a reagent in organic synthesis.

When handling 4-Methyl-2-pentenoic acid, wear appropriate personal protective equipment (PPE) including gloves, safety goggles, and a lab coat. Store the compound in a cool, dry place away from direct sunlight and incompatible materials. Use a fume hood during operations to minimize exposure. In case of spill, neutralize the acid with a base and dispose of waste according to local regulations. Refer to the Safety Data Sheet (SDS) for detailed handling and disposal information.