5-Bromo-2-(trifluoromethoxy)aniline(CAS: 886762-08-9)

5-Bromo-2-(trifluoromethoxy)aniline is a crystalline solid with a molecular weight of approximately 297.02 g/mol. It is poorly soluble in water but soluble in organic solvents such as methanol and dichloromethane. Chemically, it is relatively stable but can react with reducing agents. It has a strong absorption in the UV-visible region, making it useful for spectroscopic studies.

5-Bromo-2-(trifluoromethoxy)aniline is commonly synthesized via bromination of 2-(trifluoromethoxy)aniline. This process typically involves the use of bromine in the presence of a Lewis acid catalyst such as aluminum bromide. The reaction is performed under anhydrous conditions to ensure product purity and high yield.

5-Bromo-2-(trifluoromethoxy)aniline is used in various industries, including pharmaceuticals, where it serves as a precursor for drug intermediates. It is also utilized in the synthesis of polymers and in sensor technologies due to its unique electronic properties.

When handling 5-Bromo-2-(trifluoromethoxy)aniline, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Work should be conducted in a well-ventilated area or under a fume hood. Spills should be cleaned up immediately, and proper disposal procedures should be followed. Always refer to the safety data sheet (SDS) for detailed safety information.