2-{3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl}-5-ethyl-4-(2-phenoxyethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one(CAS: 83366-66-9)

2-{3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl}-5-ethyl-4-(2-phenoxyethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one is a crystalline compound with a high molecular weight. It has poor water solubility but good solubility in organic solvents such as DMSO. It is known for its high reactivity with nucleophiles and good stability in neutral to slightly acidic conditions.

2-{3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl}-5-ethyl-4-(2-phenoxyethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one is synthesized via a multi-step process involving the synthesis of key intermediates. Common methods include condensation reactions, followed by cyclization and alkylation steps. The use of appropriate catalysts and solvents is crucial for achieving high yields and selectivity.

2-{3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl}-5-ethyl-4-(2-phenoxyethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one is primarily used in the pharmaceutical industry for its potential therapeutic applications. It also finds application in the development of functional polymers and sensors, due to its unique chemical structure and reactivity.

When handling 2-{3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl}-5-ethyl-4-(2-phenoxyethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one, ensure the use of personal protective equipment (PPE) such as gloves, lab coat, and safety goggles. Store in a well-ventilated area and use a fume hood during synthesis. Follow standard laboratory safety protocols and keep a copy of the safety data sheet (SDS) on hand for reference.