2,4,5-Trifluorobenzaldehyde(CAS: 165047-24-5)

2,4,5-Trifluorobenzaldehyde (CAS: 165047-24-5) is a colorless to light yellow liquid with a molecular weight of approximately 170.09 g/mol. It is slightly soluble in water but soluble in common organic solvents. Chemically, it is moderately reactive, particularly towards nucleophilic and electrophilic reagents. It is often used in organic synthesis and has a melting point of -28°C and a boiling point of 150-152°C.

2,4,5-Trifluorobenzaldehyde (CAS: 165047-24-5) is typically synthesized via the reduction of 2,4,5-trifluorobenzoyl chloride with a suitable reducing agent like hydrogen over a palladium catalyst. Common methods include hydrogenation with Pd/C in the presence of methanol or ethanol. Alternatively, it can be prepared by reacting 2,4,5-trifluorobenzoyl chloride with sodium borohydride.

2,4,5-Trifluorobenzaldehyde (CAS: 165047-24-5) is used primarily in the pharmaceutical industry for the synthesis of various drugs and intermediates. It is also utilized in the polymer industry for the production of certain polymers and in the electronic industry for sensors and semiconductor fabrication. Its unique chemical properties make it a valuable reagent in organic synthesis.

When handling 2,4,5-Trifluorobenzaldehyde (CAS: 165047-24-5), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a laboratory coat. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation and skin contact. Spills should be cleaned up using appropriate absorbent materials and disposed of according to local waste disposal regulations. Always consult the Safety Data Sheet (SDS) for detailed handling instructions and emergency procedures.