3-Bromo-5-phenylpyridine(CAS: 142137-17-5)

3-Bromo-5-phenylpyridine (CAS: 142137-17-5) is a crystalline solid with a molecular weight of approximately 236.05 g/mol. It has low water solubility but good solubility in organic solvents such as DMF and DMSO. This compound is known for its moderate reactivity, particularly towards nucleophiles, making it useful in various synthetic transformations.

3-Bromo-5-phenylpyridine (CAS: 142137-17-5) is commonly synthesized via bromination of 5-phenylpyridine. This process typically involves reacting 5-phenylpyridine with N-bromosuccinimide (NBS) in an appropriate solvent under UV light. The reaction is carried out with good yield and high selectivity towards the desired brominated product.

3-Bromo-5-phenylpyridine (CAS: 142137-17-5) finds applications in pharmaceuticals, particularly as a precursor in the synthesis of antiretroviral drugs. It is also used in the development of organic semiconductors and sensors due to its unique electronic properties.

When handling 3-Bromo-5-phenylpyridine (CAS: 142137-17-5), it is essential to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize exposure. Spills should be cleaned up immediately, and disposal should follow local regulations. Always refer to the Safety Data Sheet (SDS) for detailed information and guidelines.