2-Bromo-1,4-bis(trifluoromethyl)benzene(CAS: 7617-93-8)

2-Bromo-1,4-bis(trifluoromethyl)benzene is a colorless or light yellow crystalline solid. Its molecular weight is approximately 318.07 g/mol. It is poorly soluble in water but soluble in organic solvents such as dichloromethane and acetonitrile. It is highly reactive towards nucleophiles and can undergo substitution reactions. It is a dense, volatile liquid at room temperature.

2-Bromo-1,4-bis(trifluoromethyl)benzene is typically synthesized by bromination of 1,4-bis(trifluoromethyl)benzene in the presence of a Lewis acid catalyst, such as aluminum trichloride. The reaction is carried out in anhydrous conditions and yields up to 90% of the product. The reaction is selective and provides good yield under optimized conditions.

2-Bromo-1,4-bis(trifluoromethyl)benzene is used in the pharmaceutical industry for the synthesis of certain pharmaceutical compounds. It is also utilized in the polymer industry for preparing functional polymers with enhanced properties. Additionally, it is used in the semiconductor and sensor industries for specific applications due to its unique chemical structure.

When handling 2-Bromo-1,4-bis(trifluoromethyl)benzene, it is essential to wear appropriate personal protective equipment (PPE) including gloves, safety goggles, and a laboratory coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up immediately with appropriate absorbents. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information and follow all laboratory safety guidelines.