(2,6-Difluorophenyl)acetic acid(CAS: 85068-28-6)

(2,6-Difluorophenyl)acetic acid is a crystalline solid with a molecular weight of approximately 184.12 g/mol. It has a melting point of about 83°C and is slightly soluble in water. Chemically, it is moderately reactive, particularly with bases and nucleophiles. It is used in organic synthesis and pharmaceutical applications due to its chemical stability and reactivity.

(2,6-Difluorophenyl)acetic acid is often synthesized via the acetylation of 2,6-difluorophenol using acetic anhydride in the presence of a catalyst such as sulfuric acid. The reaction yields the desired compound with good selectivity and moderate to high yield, depending on the purification method.

(2,6-Difluorophenyl)acetic acid is primarily used in the pharmaceutical industry for the synthesis of drug intermediates. It is also utilized in the polymer industry for the modification of polymers, in the sensor industry for developing chemical sensors, and in semiconductor fabrication for specific etching processes.

Handling (2,6-Difluorophenyl)acetic acid requires appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. It should be stored in a cool, dry place away from moisture and heat. In case of spill, avoid inhalation or contact with skin, and use appropriate containment and disposal methods as per the Material Safety Data Sheet (MSDS/SDS).