Octadecyl 3,4,5-trihydroxybenzoate(CAS: 10361-12-3)

Octadecyl 3,4,5-trihydroxybenzoate is a white crystalline solid with a molecular weight of approximately 324.43 g/mol. It is poorly soluble in water but soluble in organic solvents such as ethanol and acetone. The compound is relatively stable under normal laboratory conditions but can react with bases to form sodium salts. It has a melting point of around 120-125°C.

Octadecyl 3,4,5-trihydroxybenzoate is typically synthesized via the esterification of 1,2,3-propanetriol with 18-hydroxybenzoic acid in the presence of a strong acid catalyst such as sulfuric acid. The reaction yields a mixture of isomers, and the desired product is isolated by column chromatography. The yield is usually around 70-80%.

Octadecyl 3,4,5-trihydroxybenzoate finds applications in the pharmaceutical industry for its use as a surfactant and emulsifier in drug formulations. It is also used in the polymer industry as a plasticizer and in the manufacture of sensors for its optical properties. Additionally, it is employed in semiconductor manufacturing processes due to its stability and solubility characteristics.

When handling Octadecyl 3,4,5-trihydroxybenzoate, it is important to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and lab coat. It should be stored in a cool, dry place away from direct sunlight. In case of spill, use appropriate spill kits and ensure proper disposal. Always consult the Safety Data Sheet (SDS) for detailed information on safe handling and storage.