3-[(2-Ethylhexyl)oxy]-1-propanamine(CAS: 5397-31-9)

3-[(2-Ethylhexyl)oxy]-1-propanamine is a colorless liquid with a molecular weight of approximately 228.34 g/mol. It has a pKa of about 10.6 and a solubility in water of 0.3 g/100 mL. It is slightly basic and reacts with acids to form salts. It is soluble in ethanol and acetone. It does not react readily with common reagents but can undergo esterification under certain conditions.

3-[(2-Ethylhexyl)oxy]-1-propanamine is synthesized by the reduction of 3-[(2-ethoxyhexyl)oxy]-1-propanone. The reaction typically involves the use of sodium borohydride or lithium aluminum hydride as the reducing agent. The process requires careful control of temperature and reaction time to achieve high yield and selectivity.

3-[(2-Ethylhexyl)oxy]-1-propanamine is used in the pharmaceutical industry as an intermediate in the synthesis of certain drugs. It is also utilized in the polymer industry for the production of polyurethane additives and in the sensor industry for the development of chemical sensors. Additionally, it finds applications in cosmetics and personal care products due to its organoleptic properties.

When handling 3-[(2-Ethylhexyl)oxy]-1-propanamine, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a laboratory coat. It should be handled in a well-ventilated area or a fume hood. Spills should be cleaned up using appropriate absorbent materials and proper disposal methods. Safety data sheets (SDS) should be consulted for detailed handling and emergency procedures. Storage should be in a cool, dry place, away from strong acids and oxidizers.