5-Bromo-3,4-pyridinediamine(CAS: 4635-08-9)

5-Bromo-3,4-pyridinediamine (CAS: 4635-08-9) is a white crystalline solid. Its molecular weight is approximately 193.02 g/mol. It has a high solubility in organic solvents such as ethanol and acetone. Chemically, it is moderately reactive, especially under basic conditions, and susceptible to bromine substitution reactions.

5-Bromo-3,4-pyridinediamine is typically synthesized through a nucleophilic aromatic substitution reaction, where 3,4-pyridinediamine reacts with bromine in the presence of a base such as sodium hydroxide. The reaction is carried out in a polar aprotic solvent like dimethylformamide (DMF). The yield and selectivity of the reaction can be enhanced through optimization of the reaction conditions.

5-Bromo-3,4-pyridinediamine finds applications in various industries. It is used in the pharmaceutical industry for the synthesis of drugs, in the polymer industry for modifying polymer properties, and in semiconductor and sensor technology for doping and sensing applications. Its versatility makes it a valuable intermediate in these sectors.

When handling 5-Bromo-3,4-pyridinediamine (CAS: 4635-08-9), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. It should be stored in a cool, dry place away from direct sunlight and ignition sources. In case of spillage, it should be disposed of according to local regulations, and it is recommended to refer to the safety data sheet (SDS) for detailed handling instructions.