6-[(2-Amino-4-pyrimidinyl)oxy]-N-[3-(trifluoromethyl)phenyl]-1-naphthamide(CAS: 861875-60-7)

6-[(2-Amino-4-pyrimidinyl)oxy]-N-[3-(trifluoromethyl)phenyl]-1-naphthamide (CAS: 861875-60-7) is a crystalline solid with a molecular weight of approximately 508.28 g/mol. It has limited water solubility and is highly soluble in organic solvents. The compound is stable under normal laboratory conditions but may react with strong acids or bases. It shows good reactivity towards electrophiles and nucleophiles.

6-[(2-Amino-4-pyrimidinyl)oxy]-N-[3-(trifluoromethyl)phenyl]-1-naphthamide (CAS: 861875-60-7) is typically synthesized through a multi-step process involving the condensation of 1-naphthamide with 2-amino-4-pyrimidinol, followed by the introduction of the trifluoromethyl group. Common catalysts include sodium hydride, and the reaction is carried out in anhydrous conditions to ensure purity and yield.

6-[(2-Amino-4-pyrimidinyl)oxy]-N-[3-(trifluoromethyl)phenyl]-1-naphthamide (CAS: 861875-60-7) is primarily used in the pharmaceutical industry for its potential as a drug candidate. It is also explored in the electronics industry for its semi-conductive properties and in the polymer industry for its use as an additive. It has limited application in sensors and other specialized technologies.

When handling 6-[(2-Amino-4-pyrimidinyl)oxy]-N-[3-(trifluoromethyl)phenyl]-1-naphthamide (CAS: 861875-60-7), adequate personal protective equipment (PPE) such as gloves and goggles should be worn. It should be stored in a well-ventilated area and under a fume hood during preparation. Spills should be cleaned up immediately using appropriate absorbents, and proper disposal methods should be followed. Refer to the Safety Data Sheet (SDS) for specific handling and disposal guidelines.