4-Cyclohexylproline(CAS: 9002-01-1)

The physical properties of 4-Cyclohexylproline include a white crystalline form. Its molecular weight is approximately 144.24 g/mol. It has a low solubility in water but is soluble in organic solvents. Chemically, it is an amide derivative of cyclohexylalanine, making it moderately reactive with basic compounds and stable under acidic conditions.

4-Cyclohexylproline is typically synthesized by the condensation of cyclohexylamine and acrylic acid. The reaction can be catalyzed by a Lewis acid such as aluminum chloride, and the process yields a high purity product with good selectivity. The overall yield of the synthesis is around 70-80%.

4-Cyclohexylproline is used in various industries. Its amide functionality makes it useful in pharmaceuticals as a building block for drug synthesis. In the polymer industry, it serves as a monomer for developing new materials. It also finds applications in the production of sensors and semiconductors due to its structural properties.

When handling 4-Cyclohexylproline, wear protective gloves, eye protection, and a lab coat. Work in a well-ventilated area or a fume hood to minimize inhalation risks. Store it in a cool, dry place away from direct sunlight and heat sources. In case of a spill, clean it up immediately using appropriate cleaning agents and ensure proper disposal according to safety data sheets (SDS) guidelines.