2,2-Dimethyl-3-phenyl-1-propanol(CAS: 13351-61-6)

2,2-Dimethyl-3-phenyl-1-propanol has a crystalline form and a molecular weight of approximately 181.24 g/mol. It is soluble in aromatic hydrocarbons and slightly soluble in water. The compound is reactive towards acid-catalyzed transesterification and esterification. It has a melting point of 56-58°C and a boiling point of 186-188°C at 10 mmHg.

2,2-Dimethyl-3-phenyl-1-propanol is typically synthesized via a Wittig reaction between phenylmethyltriphenylphosphonium bromide and diethyl malonate. The reaction is performed in the presence of a base such as triethylamine. The yield is around 70-80%, and the product can be purified by recrystallization from ethanol or acetone.

2,2-Dimethyl-3-phenyl-1-propanol is used in the pharmaceutical industry for the synthesis of certain drug molecules. It is also utilized in the polymer industry as a monomer for the production of functionalized polymers. Additionally, it has applications in the sensor and semiconductor industries due to its unique chemical properties.

When handling 2,2-Dimethyl-3-phenyl-1-propanol, it is important to wear appropriate personal protective equipment (PPE), including gloves and safety goggles. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation risk. Spills should be cleaned up using appropriate absorbents and the material safety data sheet (SDS) should be consulted for specific disposal instructions.