Benzofuran-4-carbonitrile(CAS: 95333-17-8)

Benzofuran-4-carbonitrile is a crystalline solid with a molecular weight of approximately 145.13 g/mol. It has a low water solubility and moderate solubility in organic solvents. This compound is characterized by its reactivity, particularly towards nucleophilic substitution reactions. It is stable under normal conditions but can undergo photochemical reactions.

Benzofuran-4-carbonitrile is typically synthesized through the reaction of benzofuran with hydrocyanic acid or its derivatives. This process can also be achieved through the nitrile addition to the furan ring using appropriate conditions, often involving a catalyst to enhance selectivity and yield. The method can vary depending on the desired scale and purity requirements.

Benzofuran-4-carbonitrile is used in various industries. It finds applications in pharmaceuticals, where it serves as a precursor for the synthesis of certain drugs. It is also utilized in the polymer industry for enhancing properties of plastics and in the development of sensors and semiconductor materials due to its unique chemical properties.

When handling Benzofuran-4-carbonitrile, it is essential to wear personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize exposure. Disposal should be done according to local regulations, and spills should be cleaned up with appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed instructions.