Methyl 2-methyl-2-propanyl malonate(CAS: 42726-73-8)

Methyl 2-methyl-2-propanyl malonate is a colorless liquid with a molecular weight of 148.21 g/mol. It has a boiling point of 196°C and a flash point of 74°C. The compound is soluble in ethanol and acetone but insoluble in water. It is reactive towards bases and can undergo esterification and hydrolysis reactions.

Methyl 2-methyl-2-propanyl malonate can be synthesized via the Michael addition of methyl allyl malonate to 1-bromopropane. This process involves the use of a Lewis acid catalyst like aluminum chloride (AlCl3) and requires careful control of temperature and stirring to ensure high yield and selectivity.

Methyl 2-methyl-2-propanyl malonate is used in the pharmaceutical industry for the synthesis of certain compounds, in the polymer industry as a plasticizer, and in the sensor industry for the detection of specific gases. It is also used in the semiconductor industry as a cleaning agent.

When handling Methyl 2-methyl-2-propanyl malonate, wear appropriate personal protective equipment (PPE) including chemical-resistant gloves, safety goggles, and a lab coat. Ensure adequate ventilation and use a fume hood during operations. Spills should be cleaned up immediately using absorbent materials, and the area should be well-ventilated. Refer to the Safety Data Sheet (SDS) for detailed safety information.