(1'r,4'r)-4'-(3,4-Difluorophenyl)-1,1'-bi(cyclohexyl)-4-one(CAS: 147622-85-3)

(1'r,4'r)-4'-(3,4-Difluorophenyl)-1,1'-bi(cyclohexyl)-4-one is a white crystalline solid with a molecular weight of 314.21 g/mol. It is slightly soluble in common organic solvents and has limited reactivity under normal conditions. This compound can form intermolecular hydrogen bonds, contributing to its crystalline structure.

(1'r,4'r)-4'-(3,4-Difluorophenyl)-1,1'-bi(cyclohexyl)-4-one is commonly synthesized via a multistep process involving the reaction of 3,4-difluorobenzaldehyde with 1,1'-bi(cyclohexyl)-4-one. The reaction is often catalyzed with a palladium-based catalyst, achieving high selectivity and yield.

(1'r,4'r)-4'-(3,4-Difluorophenyl)-1,1'-bi(cyclohexyl)-4-one finds application in pharmaceuticals and polymer synthesis due to its unique chemical structure. It is used in the development of certain pharmaceuticals and as a precursor in the fabrication of advanced polymers with specific properties.

When handling (1'r,4'r)-4'-(3,4-Difluorophenyl)-1,1'-bi(cyclohexyl)-4-one, it is essential to use appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation. Spills should be handled carefully, and the Material Safety Data Sheet (MSDS) should be consulted for specific guidelines.