5-(Chloromethyl)-2-furaldehyde(CAS: 1623-88-7)

5-(Chloromethyl)-2-furaldehyde is a colorless to light yellow liquid. It has a molecular weight of approximately 155.54 g/mol and a boiling point of 102-103°C. This compound is soluble in ethanol and acetone, but slightly soluble in water. It is highly reactive due to the presence of the aldehyde and chloromethyl groups.

5-(Chloromethyl)-2-furaldehyde is commonly synthesized by the reaction of formaldehyde with chloroacetaldehyde. This process often involves using acid catalysts like hydrochloric acid to improve reaction selectivity and yield. The final product is isolated and purified through distillation.

5-(Chloromethyl)-2-furaldehyde is used in various industries, including pharmaceuticals for the synthesis of certain drugs, polymers for specific applications requiring functional groups, and as a precursor in the manufacturing of sensors and semiconductors due to its chemical reactivity and functional groups.

When handling 5-(Chloromethyl)-2-furaldehyde, proper personal protective equipment (PPE) is essential, including gloves, goggles, and a lab coat. Work should only be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up using appropriate absorbents and disposed of according to local regulations. Safety data sheets (SDS) should be consulted for detailed handling and disposal procedures.