Methyl 4-amino-3-methoxybenzoate(CAS: 41608-64-4)

Methyl 4-amino-3-methoxybenzoate (CAS: 41608-64-4) is a white to off-white crystalline solid with a molecular weight of approximately 219.22 g/mol. It has a solubility of about 3.5 g/L in water and is practically insoluble in ethanol. This compound is moderately reactive and susceptible to hydrolysis under basic conditions. It has a melting point around 79-81°C and is stable under normal laboratory conditions, but care should be taken to avoid prolonged exposure to moisture.

Methyl 4-amino-3-methoxybenzoate (CAS: 41608-64-4) can be synthesized via the esterification of 4-amino-3-methoxybenzoic acid with methanol in the presence of a suitable catalyst such as sulfuric acid or p-toluenesulfonic acid. The reaction is typically carried out at a temperature of around 80°C, with an isolated yield of approximately 80-85%. The reaction is selective and proceeds with good stereoselectivity.

Methyl 4-amino-3-methoxybenzoate (CAS: 41608-64-4) is used in the pharmaceutical industry as an intermediate in the synthesis of certain drugs. It is also utilized in the polymer industry as a stabilizer and in the production of dyes. Additionally, it can be used in the production of sensors and as a component in some semiconductor materials due to its specific chemical properties.

When handling Methyl 4-amino-3-methoxybenzoate (CAS: 41608-64-4), appropriate personal protective equipment (PPE) should be worn, including gloves, safety goggles, and a lab coat. This compound should be stored in a well-ventilated area and away from moisture. Fume hoods should be used during its manipulation to minimize inhalation risk. In the event of a spill, it should be cleaned up using appropriate absorbent materials and the area should be thoroughly washed with water. Consult the Material Safety Data Sheet (MSDS) for detailed spill and emergency response procedures.