1,7-naphthyridin-8-ol(CAS: 67967-11-7)

1,7-Naphthyridin-8-ol (CAS: 67967-11-7) is a crystalline compound with a molecular weight of approximately 165.17 g/mol. It has a solubility of about 1.4 g/L in water at 25°C. Chemically, it is mildly reactive with common bases and possesses good stability under neutral to slightly basic conditions. It is used in various applications due to its structural properties.

1,7-Naphthyridin-8-ol (CAS: 67967-11-7) is typically synthesized via the condensation of 1-naphthol and 3,5-dinitrobenzoic acid, followed by reduction and deprotection steps. The reaction involves the use of sodium bisulfite as a reductant and ethanol as a solvent, yielding the compound with a reported yield of 75%. The synthesis is selective and efficient.

1,7-Naphthyridin-8-ol (CAS: 67967-11-7) is used in various industries, including pharmaceuticals for the synthesis of certain medications, polymers for enhancing material properties, and sensors for detecting specific analytes. Its unique chemical structure makes it valuable in these applications.

When handling 1,7-naphthyridin-8-ol (CAS: 67967-11-7), it is crucial to wear protective equipment including gloves, goggles, and lab coats. Store it in a fume hood to minimize inhalation risk. In case of a spill, use appropriate absorbent materials and follow local safety guidelines. Always refer to the Safety Data Sheet (SDS) for detailed information on handling and disposal.