Ethyl 2-amino-3-thiophenecarboxylate(CAS: 31891-06-2)

Ethyl 2-amino-3-thiophenecarboxylate (CAS: 31891-06-2) is a crystalline solid with a molecular weight of approximately 205.25 g/mol. It has a low solubility in water but is soluble in organic solvents such as ethanol and acetone. The compound is known for its reactivity, particularly towards nucleophiles and electrophiles, making it useful in various chemical reactions.

Ethyl 2-amino-3-thiophenecarboxylate (CAS: 31891-06-2) is typically synthesized via a multistep process involving the reaction of thiophene-3-carboxylic acid with ethylamine. The synthesis involves protecting the carboxyl group, amide formation, and deprotection steps. Catalysts such as HOBt (Hydroxylamine Hydrochloride) and DMAP (4-Dimethylaminopyridine) are often used to improve yield and selectivity.

Ethyl 2-amino-3-thiophenecarboxylate (CAS: 31891-06-2) is used in various industries, particularly in pharmaceuticals for developing new drug candidates, in polymers for enhancing material properties, and in sensors for detecting specific chemical compounds. It is also used in the synthesis of semiconductors for electronic devices.

When handling Ethyl 2-amino-3-thiophenecarboxylate (CAS: 31891-06-2), it is important to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be performed in a well-ventilated area or fume hood. Spills should be contained and disposed of according to safety data sheet (SDS) guidelines. Always consult the SDS for detailed handling and storage instructions.