Acemetacin(CAS: 53164-05-9)

Acemetacin (CAS: 53164-05-9) is a white, crystalline powder with a molecular weight of approximately 359.34 g/mol. It is slightly soluble in water and freely soluble in ethanol and methanol. Chemically, it is highly reactive towards basic conditions and exhibits limited solubility in acidic media.

Acemetacin (CAS: 53164-05-9) is synthesized through a multi-step process involving the reaction of 2-aminobenzophenone with 2,3-dichloro-5-methylbenzene, followed by acetylation and cyclization. Common catalysts include aluminum chloride, and the process yields a high purity product with good selectivity.

Acemetacin (CAS: 53164-05-9) is primarily used in the pharmaceutical industry as a nonsteroidal anti-inflammatory drug (NSAID). It is also applied in the synthesis of certain polymers and as a component in some sensor devices due to its reactivity and solubility properties.

When handling Acemetacin (CAS: 53164-05-9), wear appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coat. Work in a well-ventilated area or fume hood, as it is sensitive to basic conditions. In case of spill, follow the guidelines in the safety data sheet (SDS) and clean up using appropriate absorbent materials.