6-Methyl-1H-indol-4-ol(CAS: 61545-41-3)

6-Methyl-1H-indol-4-ol is an organic compound with a molecular weight of approximately 144.21 g/mol. It exists as a crystalline solid with a melting point of about 152-154°C. The compound is sparingly soluble in water but soluble in organic solvents like methanol and ethanol. It is moderately reactive, particularly towards electrophilic aromatic substitution reactions. Its solubility in water at 25°C is around 0.2 g/L.

6-Methyl-1H-indol-4-ol can be synthesized through the reduction of 6-methyl-1H-indole-4-carbaldehyde using catalytic hydrogenation with a palladium catalyst. Alternatively, it can be prepared by the reduction of 6-methyl-1H-indole-4-carboxaldehyde. The yield and selectivity are typically high, and the method is efficient under mild conditions.

6-Methyl-1H-indol-4-ol is utilized in the pharmaceutical industry for the synthesis of certain drugs. It serves as an intermediate in the production of indole derivatives, which have applications in the development of new medicines. Additionally, it finds use in the production of various chemical intermediates and in research related to organic synthesis and materials science.

When handling 6-Methyl-1H-indol-4-ol (CAS: 61545-41-3), proper personal protective equipment (PPE) such as gloves, goggles, and a laboratory coat should be worn. Work should be conducted in a well-ventilated area or a fume hood to prevent inhalation. Spills should be cleaned up immediately using appropriate absorbent materials, and the area should be well-ventilated. Always consult the Material Safety Data Sheet (MSDS) for detailed safety information and emergency procedures.