1,3-Benzodioxol-5-ylacetic acid(CAS: 2861-28-1)

1,3-Benzodioxol-5-ylacetic acid has a white or off-white crystalline form. Its molecular weight is approximately 184.17 g/mol. The compound is slightly soluble in water but soluble in common organic solvents like acetone and dimethylformamide. It is moderately reactive, particularly with strong bases and reducing agents. Accurate pH measurements show that it has a pKa value around 4.1.

1,3-Benzodioxol-5-ylacetic acid can be synthesized via a multi-step process starting from 1,3-benzenedione. The key steps involve the condensation of 1,3-benzenedione with 5-hydroxy-1,3-dioxolane followed by acetylation. This method provides a yield of about 75% and uses mild conditions to ensure selectivity and purity of the final product.

1,3-Benzodioxol-5-ylacetic acid is primarily used in the pharmaceutical industry for the synthesis of various drugs. It is also used in the polymer industry as a monomer for the preparation of certain polymers. Additionally, it has applications in the sensor and semiconductor industries due to its chemical stability and reactivity.

When handling 1,3-Benzodioxol-5-ylacetic acid, it is important to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. It should be stored in a cool, dry place away from heat sources and incompatible materials. In case of a spill, it should be cleaned up using absorbent material and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and storage instructions.