Pregna-4,6-diene-3,20-dione(CAS: 1162-56-7)

Pregna-4,6-diene-3,20-dione (CAS: 1162-56-7) is a colorless or white crystalline solid with a molecular weight of 282.37 g/mol. It has a low solubility in water but is soluble in organic solvents like ethanol and acetone. Chemically, it is relatively stable but can undergo reactions such as hydrolysis and oxidation under certain conditions.

Pregna-4,6-diene-3,20-dione can be synthesized via the Diels-Alder reaction between maleic anhydride and 20-dehydrocholesterol. The reaction is catalyzed by Lewis acids such as boron trifluoride. The yield and selectivity are high, making it a common method for industrial production.

Pregna-4,6-diene-3,20-dione is primarily used in the pharmaceutical industry as an intermediate in the synthesis of steroid drugs. It is also utilized in the production of certain polymers and in the development of sensors for detecting specific biological compounds.

When handling Pregna-4,6-diene-3,20-dione, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be carried out in a fume hood to minimize exposure. Spills should be cleaned up using appropriate methods, and the area should be well-ventilated. Always consult the Safety Data Sheet (SDS) for specific handling instructions and emergency procedures.