Methyl (2-chloroethoxy)acetate(CAS: 83881-47-4)

Methyl (2-chloroethoxy)acetate (CAS: 83881-47-4) is a colorless to slightly yellow liquid with a molecular weight of approximately 166.59 g/mol. It has a high solubility in organic solvents but is only slightly soluble in water. The compound is moderately reactive, showing partial reactivity towards nucleophiles and basic conditions. It has a melting point of -17°C and a boiling point of 81°C.

Methyl (2-chloroethoxy)acetate (CAS: 83881-47-4) is typically synthesized via the reaction of methyl acetate with ethylene oxide in the presence of a phase-transfer catalyst, such as tetra-n-butylammonium bromide (TBAB). The reaction is carried out under mild conditions, yielding a high degree of selectivity and a good yield of the desired product.

Methyl (2-chloroethoxy)acetate (CAS: 83881-47-4) is used in the pharmaceutical industry as a precursor for the synthesis of various drugs. It is also utilized in the polymer industry for the production of certain polymers and in the electronics industry for applications in sensors and semiconductors.

When handling Methyl (2-chloroethoxy)acetate (CAS: 83881-47-4), it is important to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. This compound should be stored in a cool, dry, well-ventilated area away from direct sunlight. In case of a spill, it should be handled using appropriate safety protocols and cleaned up using absorbent materials. Emergency response procedures should be followed, and the Material Safety Data Sheet (MSDS) or Safety Data Sheet (SDS) should be consulted for detailed information.