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Abemaciclib(CAS: 1231929-97-7)
CAS Number
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Basic Information
Molecular Formula
C27H32F2N8
Molecular Weight
506.61 g/mol
Physical Properties
Boiling Point
689.3±65.0°C at 760 mmHg
Chemical Identifiers
SMILES
CCN1CCN(CC1)CC2=CN=C(C=C2)NC3=NC=C(C(=N3)C4=CC5=C(C(=C4)F)N=C(N5C(C)C)C)F
InChIKey
UZWDCWONPYILKI-UHFFFAOYSA-N
Database References
MDL Number
MFCD22665744
FAQ
Abemaciclib is a selective CDK4/6 inhibitor. It has a chemical formula of C28H28N6O5 and is used in the treatment of certain types of breast cancer in combination with other medications.
Abemaciclib is primarily used in the treatment of hormone receptor-positive, HER2-negative advanced or metastatic breast cancer in combination with fulvestrant. It is also used in certain clinical trials for other types of cancer.
Abemaciclib is generally safe when used as directed. However, it may cause side effects such as diarrhea, fatigue, and neutropenia. Patients should avoid potential interactions with other medications and follow medical advice for monitoring and management of side effects.
Abemaciclib should be stored at room temperature (15°C to 30°C), away from direct light and moisture. It should be kept in a tightly closed container to protect it from air and light. Avoid storing it in high humidity areas or direct sunlight.
Safety Notice
Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.
Always follow proper handling procedures
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