2-Bromo-4-chloro-1-nitrobenzene(CAS: 63860-31-1)

2-Bromo-4-chloro-1-nitrobenzene (CAS: 63860-31-1) is a crystalline solid with a molecular weight of approximately 230.02 g/mol. It has poor water solubility but is soluble in organic solvents like ethanol and acetone. This compound is known for its reactivity, particularly in electrophilic aromatic substitution reactions. It is used in the synthesis of various aromatic compounds and pharmaceutical intermediates.

2-Bromo-4-chloro-1-nitrobenzene can be synthesized through the nitration of 4-chlorobromobenzene. The reaction typically involves the use of concentrated nitric acid and sulfuric acid as a catalyst. The process requires careful control of temperature and concentration to achieve high selectivity and yield. This method is commonly used in academic and industrial settings for the preparation of this aromatic compound.

2-Bromo-4-chloro-1-nitrobenzene is primarily used in the pharmaceutical and chemical industries as an intermediate in the synthesis of various drugs and organic compounds. It is also utilized in the manufacturing of dyes and pigments. Its versatility in organic synthesis makes it a valuable reagent in both academic and industrial research.

When handling 2-Bromo-4-chloro-1-nitrobenzene (CAS: 63860-31-1), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a laboratory coat to protect against skin contact and inhalation. This compound should be handled in a well-ventilated area or a fume hood to minimize exposure. Spills should be immediately cleaned up using appropriate absorbents, and the area should be flushed with water. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.