Dihydrostreptomycin sulfate(CAS: 5490-27-7)

Dihydrostreptomycin sulfate has a crystalline form. Its molecular weight is approximately 1011.33 g/mol. The compound is moderately soluble in water and slightly soluble in ethanol. It is chemically stable under normal conditions but reacts with strong acids to form dihydrostreptomycin. It is also susceptible to hydrolysis under basic conditions.

Dihydrostreptomycin sulfate is synthesized through the modification of streptomycin. The process involves the reduction of streptomycin sulfate to dihydrostreptomycin sulfate using sodium borohydride as a catalyst. The reaction is highly selective and yields a high percentage of the desired product. The product is then converted to sulfate by reacting with sulfuric acid in the presence of a suitable solvent.

Dihydrostreptomycin sulfate is primarily used in the pharmaceutical industry for producing antibiotics. It is also utilized in the agricultural sector as a fungicide. Additionally, it has applications in research and development for studying antibiotic resistance and in biotechnology for enhancing microbial growth and metabolism.

When handling Dihydrostreptomycin sulfate, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to avoid inhalation. Spills should be cleaned up immediately using appropriate methods as detailed in the safety data sheet (SDS). Storage should be in a cool, dry place away from heat sources and incompatible materials.