Methyl 3-amino-4-iodobenzoate(CAS: 412947-54-7)

Methyl 3-amino-4-iodobenzoate (CAS: 412947-54-7) is a white crystalline solid. Its molecular weight is approximately 302.01 g/mol. It has a low water solubility, making it difficult to dissolve in water. The compound is highly reactive towards nucleophiles due to the presence of the amino and iodide groups. It is also sensitive to light and air, necessitating storage under inert conditions.

Methyl 3-amino-4-iodobenzoate (CAS: 412947-54-7) can be synthesized via a two-step process. Firstly, 4-iodobenzoic acid is treated with methylamine to form the amide intermediate. In the second step, this intermediate is converted to the methyl 3-amino-4-iodobenzoate by hydrolysis. Commonly, palladium-based catalysts are used to improve the yield and selectivity of the reaction.

Methyl 3-amino-4-iodobenzoate (CAS: 412947-54-7) is primarily used in the pharmaceutical industry for the synthesis of certain drug intermediates. It is also of interest in the polymer industry for the development of functional polymers and in the sensor industry for its unique reactivity towards nucleophiles.

When handling Methyl 3-amino-4-iodobenzoate (CAS: 412947-54-7), it is important to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. This compound should be handled in a fume hood or a well-ventilated area to minimize exposure to vapors. Spills should be cleaned up immediately using appropriate absorbent materials, and the area should be well-ventilated. Always refer to the Safety Data Sheet (SDS) for more detailed information on safe handling and disposal.