Methyl 4-nitro-1H-pyrazole-3-carboxylate(CAS: 138786-86-4)

Methyl 4-nitro-1H-pyrazole-3-carboxylate (CAS: 138786-86-4) is a crystalline solid with a molecular weight of approximately 219.12 g/mol. It is slightly soluble in water and more soluble in organic solvents like methanol and ethanol. Chemically, it is reactive towards nucleophiles and can undergo substitution reactions. It is also susceptible to hydrolysis under basic conditions.

Methyl 4-nitro-1H-pyrazole-3-carboxylate (CAS: 138786-86-4) is commonly synthesized via a multi-step process involving the nitration of 4-hydroxy-1H-pyrazole-3-carboxylic acid methyl ester followed by esterification. The synthesis typically uses nitric acid as the oxidizing agent and sulfuric acid as a catalyst. The reaction is carried out under acidic conditions and the product is isolated by recrystallization.

Methyl 4-nitro-1H-pyrazole-3-carboxylate (CAS: 138786-86-4) is used in the pharmaceutical industry for the synthesis of certain medicinal compounds. It also finds applications in the synthesis of materials for sensors and semiconductors, particularly in the development of organic electronic devices.

When handling Methyl 4-nitro-1H-pyrazole-3-carboxylate (CAS: 138786-86-4), safety goggles and gloves should be worn to prevent skin contact and eye irritation. It should be stored in a well-ventilated area and away from heat sources and strong acids. In case of a spill, it should be immediately cleaned up using appropriate absorbent materials and the area should be well-ventilated. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.